Matchup Overview

The Buffalo Bills and Detroit Lions have met 15 times in NFL. Buffalo Bills hold a clear edge in the all-time series, 8–7. Buffalo Bills have been dominant in recent meetings, winning 5 of their last 5. Their most recent matchup ended 48–42 in favor of Buffalo Bills on December 15, 2024. They are scheduled to meet again on September 18, 2026 at Highmark Stadium, Orchard Park.

Next Meeting

Detroit LionsAway

@Fri, Sep 1812:15 AM UTCWeek Week 2Highmark Stadium, Orchard Park

Buffalo BillsHome

All-Time Head-to-Head

Showing 15 games from available historical data.

Date	Season	Away	Score	Home
Dec 15, 24	2024 WWeek 15	BUF	48–42	DET
Nov 24, 22	2022 WWeek 12	BUF	28–25	DET
Aug 13, 21	2021	BUF	16–15	DET
Aug 23, 19	2019	BUF	24–20	DET
Dec 16, 18	2018	DET	13–14	BUF
Aug 31, 17	2017	DET	17–27	BUF
Sep 1, 16	2016	BUF	0–31	DET
Sep 3, 15	2015	BUF	10–17	DET
Oct 5, 14	2014	BUF	17–14	DET
Aug 28, 14	2014	DET	23–0	BUF
Aug 29, 13	2013	DET	35–13	BUF
Aug 30, 12	2012	BUF	32–38	DET
Sep 1, 11	2011	DET	16–6	BUF
Nov 14, 10	2010	DET	12–14	BUF
Sep 2, 10	2010	BUF	23–28	DET