NFL · All-Time Matchup
Carolina Panthers
VS
San Francisco 49ers
Carolina Panthers vs San Francisco 49ers:All-Time Matchup History
Matchup Overview
The Carolina Panthers and San Francisco 49ers have met 8 times in NFL. The all-time series is perfectly even at 4–4. San Francisco 49ers have had the upper hand recently, going 3–2 in their last 5 meetings. Their most recent matchup ended 20–9 in favor of San Francisco 49ers on November 25, 2025.
Next Meeting
No upcoming game scheduled between these teams this season.
All-Time Head-to-Head
Showing 8 games from available historical data.
| Date | Away | Score | Home |
|---|---|---|---|
| Nov 25, 25 | CAR | 9–20 | SF |
| Oct 9, 22 | SF | 37–15 | CAR |
| Oct 27, 19 | CAR | 13–51 | SF |
| Sep 10, 17 | CAR | 23–3 | SF |
| Sep 18, 16 | SF | 27–46 | CAR |
| Jan 12, 14 | SF | 23–10 | CAR |
| Nov 10, 13 | CAR | 10–9 | SF |
| Oct 24, 10 | SF | 20–23 | CAR |
Overall Record
since 2010
Carolina Panthers
4San Francisco 49ers
48 games in available data
Last 5 Meetings
CAR9
@Nov 25
20SF
SF37
@Oct 9
15CAR
CAR13
@Oct 27
51SF
CAR23
@Sep 10
3SF
SF27
@Sep 18
46CAR