NFL · All-Time Matchup
Houston Texans
VS
San Francisco 49ers
Houston Texans vs San Francisco 49ers:All-Time Matchup History
Matchup Overview
The Houston Texans and San Francisco 49ers have met 6 times in NFL regular-season and playoff games since 2005. San Francisco 49ers hold a dominant all-time edge, leading the series 4–2. San Francisco 49ers have had the upper hand recently, going 3–2 in their last 5 meetings. Their most recent matchup ended 26–15 in favor of Houston Texans on October 26, 2025.
Next Meeting
No upcoming game scheduled between these teams this season.
All-Time Head-to-Head
Showing 6 games from available historical data. Preseason games are not included.
| Date | Away | Score | Home |
|---|---|---|---|
| Oct 26, 25 | SF | 15–26 | HOU |
| Jan 2, 22 | HOU | 7–23 | SF |
| Dec 10, 17 | SF | 26–16 | HOU |
| Oct 6, 13 | HOU | 3–34 | SF |
| Oct 24, 09 | SF | 21–24 | HOU |
| Dec 31, 05 | HOU | 17–20 | SF |
Games before the 2010 season: Data from FiveThirtyEight, used under the MIT License and limited to today's franchises.
Overall Record
since 2005
Houston Texans
2San Francisco 49ers
46 games in available data
Last 5 Meetings
SF15
@Oct 26
26HOU
HOU7
@Jan 2
23SF
SF26
@Dec 10
16HOU
HOU3
@Oct 6
34SF
SF21
@Oct 24
24HOU