Matchup Overview

The Los Angeles Chargers and San Francisco 49ers have met 18 times in NFL. San Francisco 49ers hold a dominant all-time edge, leading the series 12–6. San Francisco 49ers have been dominant in recent meetings, winning 4 of their last 5. Their most recent matchup ended 41–17 in favor of San Francisco 49ers on August 21, 2026. They are scheduled to meet again on December 18, 2026 at SoFi Stadium, Inglewood.

Next Meeting

San Francisco 49ersAway

@Fri, Dec 181:15 AM UTCWeek Week 15SoFi Stadium, Inglewood

Los Angeles ChargersHome

All-Time Head-to-Head

Showing 18 games from available historical data.

Date	Season	Away	Score	Home
Aug 21, 26	2026 WWeek 2	SF	41–17	LAC
Aug 24, 25	2025 WWeek 3	LAC	23–30	SF
Aug 26, 23	2023 WWeek 3	LAC	23–12	SF
Nov 14, 22	2022 WWeek 10	LAC	16–22	SF
Aug 22, 21	2021	SF	15–10	LAC
Aug 30, 19	2019	LAC	27–24	SF
Sep 30, 18	2018	SF	27–29	LAC
Aug 31, 18	2018	LAC	23–21	SF
Sep 1, 17	2017	LAC	13–23	SF
Sep 2, 16	2016	SF	31–21	LAC
Sep 4, 15	2015	LAC	12–14	SF
Dec 21, 14	2014	LAC	38–35	SF
Aug 24, 14	2014	LAC	7–21	SF
Aug 30, 13	2013	SF	41–6	LAC
Aug 31, 12	2012	LAC	3–35	SF
Sep 2, 11	2011	SF	20–17	LAC
Dec 17, 10	2010	SF	7–34	LAC
Sep 3, 10	2010	LAC	14–17	SF